ANKRD55

Across TCGA patient cohorts, ANKRD55 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD55-associated genes across cancer lineages are TFRC, Annexin-1, and Src_pY527. Each is linked with ANKRD55 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD55-to-partner and partner-to-ANKRD55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by ANKRD55-low versus ANKRD55-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD55→partner) and Y-score (partner→ANKRD55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.584	+2.000	.004	.030	3	3
UCEC	Annexin-1 →	+0.523	+2.604	.009	.005	3	2
UCEC	Src_pY527 →	-0.494	-2.574	.002	.010	3	2
UCEC	ASNS →	+0.365	+3.169	.008	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+1.002	+2.827	<.001	.001	3	2
UCEC	Chk2_pT68 →	-0.160	-2.295	.025	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

TFRC by ANKRD55 expression — UCEC

Explore this box plot interactively →