ANKRD55

Across TCGA cell cohorts, ANKRD55 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKRD55-associated genes across cancer lineages are IL2, MTRNR2L10, and RPE65. Each is linked with ANKRD55 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD55-to-partner and partner-to-ANKRD55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL2 grouped by ANKRD55-low versus ANKRD55-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD55→partner) and Y-score (partner→ANKRD55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IL2 →	+0.028	+5.196	<.001	.005	3	1
OVARY	MTRNR2L10 →	+0.006	+5.196	<.001	.005	3	1
BLOOD_Leukemia	RPE65 →	+0.045	+3.475	<.001	.006	3	1
BLOOD_Leukemia	NT5C1A →	+0.206	+4.177	<.001	.001	3	1
BLOOD_Leukemia	MYOG →	+0.034	+4.091	<.001	.002	3	1
BLOOD_Leukemia	HCN4 →	+0.032	+4.177	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

IL2 by ANKRD55 expression — OVARY

Explore this box plot interactively →