ANKRD54

Across TCGA patient cohorts, ANKRD54 mutation is significantly associated with the RNA expression of many other genes, with 797 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD54-associated genes across cancer lineages are RNU6-147P, LINC02353, and RN7SKP289. Each is linked with ANKRD54 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD54-to-partner and partner-to-ANKRD54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-147P grouped by ANKRD54-low versus ANKRD54-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD54→partner) and Y-score (partner→ANKRD54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-147P →	+0.369	+5.513	<.001	.004	3	2
CESC	LINC02353 →	+0.063	+5.669	<.001	.003	3	2
CESC	RN7SKP289 →	+0.125	+7.584	<.001	<.001	3	2
UCEC	ESS2 →	+0.401	+3.617	<.001	.001	3	1
UCEC	CRYBB2P1 →	+0.506	+3.592	.005	.001	3	1
UCEC	CHKB →	+0.579	+3.467	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 797 associations by consensus.

RNU6-147P by ANKRD54 expression — SKCM

Explore this box plot interactively →