ANKRD54

Across TCGA patient cohorts, ANKRD54 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD54-associated genes across cancer lineages are CLP, Adipocytes, and Neurons. Each is linked with ANKRD54 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD54-to-partner and partner-to-ANKRD54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by ANKRD54-low versus ANKRD54-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD54→partner) and Y-score (partner→ANKRD54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.066	-1.957	.018	.032	3	1
UCEC	Adipocytes →	+0.018	+2.507	.021	.004	3	1
UCEC	Neurons →	-0.020	-2.418	.016	.020	3	1
UCEC	CD8+ naive T-cells →	+0.033	+3.186	.006	.010	2	1
UCEC	pro B-cells →	-0.136	-3.305	.005	.010	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CLP by ANKRD54 expression — UCEC

Explore this box plot interactively →