ANKRD53

Across TCGA cell cohorts, ANKRD53 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,701 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ANKRD53-associated GO terms across cancer lineages are Golgi vesicle transport, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with ANKRD53 in more than 14 cancer types. Because this analysis shows association rather than direction, both ANKRD53-to-partner and partner-to-ANKRD53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by ANKRD53-low versus ANKRD53-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD53→partner) and Y-score (partner→ANKRD53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Golgi vesicle transport →	+0.067	+0.331	.001	.003	3	15
OESOPHAGUS	Regulation of myoblast fusion →	+0.151	+0.563	.002	.003	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.164	+0.441	<.001	.003	3	13
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.161	+0.445	<.001	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.046	+0.201	<.001	.004	3	13
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.144	+0.559	.003	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,701 associations by consensus.

Golgi vesicle transport by ANKRD53 expression — OESOPHAGUS

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