ANKRD52

Across TCGA pan-cancer cohorts, ANKRD52 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ANKRD52 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ANKRD52 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ANKRD52 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, GBM, and LSCC are the cancer types where ANKRD52 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	1.000	0.457	.011	20	view →
GBM	OS	Tertile	All	0.288	0.498	.017	12	view →
LSCC	DFS	Median	All	0.725	0.849	.028	2	view →
CCRCC	DFS	Median	II,III,IV	0.625	0.828	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ANKRD52–UCEC (OS)

Open the UCEC breakdown →