ANKRD52

Across TCGA patient cohorts, ANKRD52 mutation is significantly associated with the RNA expression of many other genes, with 2,869 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD52-associated genes across cancer lineages are LINC00869, APEH, and PBK. Each is linked with ANKRD52 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD52-to-partner and partner-to-ANKRD52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00869 grouped by ANKRD52-low versus ANKRD52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD52→partner) and Y-score (partner→ANKRD52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC00869 →	-0.551	-2.297	<.001	.001	3	3
UCEC	APEH →	+0.368	+1.777	.007	.002	3	3
UCEC	PBK →	+0.678	+2.247	.003	.001	3	3
UCEC	LETM1 →	+0.508	+2.101	<.001	<.001	3	3
UCEC	NIPA1 →	+0.802	+2.080	<.001	<.001	3	3
UCEC	GPHN →	+0.379	+1.773	.005	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,869 associations by consensus.

LINC00869 by ANKRD52 expression — UCEC

Explore this box plot interactively →