ANKRD52

Across TCGA patient cohorts, ANKRD52 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD52-associated genes across cancer lineages are Bak, JNK_pT183_Y185, and MSH6. Each is linked with ANKRD52 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD52-to-partner and partner-to-ANKRD52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bak grouped by ANKRD52-low versus ANKRD52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD52→partner) and Y-score (partner→ANKRD52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bak →	+0.212	+2.087	.014	.005	3	3
UCEC	JNK_pT183_Y185 →	-0.175	-2.584	.002	.010	3	2
UCEC	MSH6 →	-0.399	-2.807	<.001	.002	3	2
UCEC	PCNA →	+0.246	+1.440	<.001	.024	3	2
COAD	Caspase-7-cleavedD198 →	+1.414	+3.016	<.001	.018	3	2
UCEC	c-Kit →	-0.189	-2.446	.019	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Bak by ANKRD52 expression — UCEC

Explore this box plot interactively →