ANKRD50

Across TCGA patient cohorts, ANKRD50 protein abundance is significantly associated with the RNA expression of many other genes, with 8,560 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANKRD50-associated genes across cancer lineages are SOCS2, EDNRA, and NPNT. Each is linked with ANKRD50 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD50-to-partner and partner-to-ANKRD50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD50 versus SOCS2 in CCRCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD50→partner) and Y-score (partner→ANKRD50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SOCS2 →	+0.939	+0.295	<.001	<.001	3	4
CCRCC	EDNRA →	+0.942	+0.280	<.001	<.001	3	4
BRCA	NPNT →	+1.753	+0.335	<.001	<.001	3	4
LSCC	PCDH7 →	+1.413	+0.392	<.001	<.001	3	4
UCEC	GLI3 →	+1.258	+0.206	<.001	.008	3	3
GBM	HOXD3 →	+1.251	+0.279	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,560 associations by consensus.

ANKRD50 vs SOCS2 — CCRCC

Explore this scatter interactively →