ANKRD50

Across TCGA patient cohorts, ANKRD50 mutation is significantly associated with the RNA expression of many other genes, with 4,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD50-associated genes across cancer lineages are TPPP3, UBR7, and HADH. Each is linked with ANKRD50 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD50-to-partner and partner-to-ANKRD50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPPP3 grouped by ANKRD50-low versus ANKRD50-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD50→partner) and Y-score (partner→ANKRD50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TPPP3 →	-0.976	-2.087	.003	.005	3	4
UCEC	UBR7 →	+0.478	+1.705	<.001	<.001	3	4
UCEC	HADH →	+0.459	+1.270	<.001	.001	3	4
UCEC	CHEK1 →	+0.504	+1.413	<.001	<.001	3	3
UCEC	DLAT →	+0.503	+1.392	<.001	<.001	3	3
UCEC	SUPV3L1 →	+0.252	+1.403	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,799 associations by consensus.

TPPP3 by ANKRD50 expression — UCEC

Explore this box plot interactively →