ANKRD50

Across TCGA patient cohorts, ANKRD50 mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD50-associated genes across cancer lineages are Caspase-7-cleavedD198, ATM, and FASN. Each is linked with ANKRD50 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD50-to-partner and partner-to-ANKRD50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ANKRD50-low versus ANKRD50-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD50→partner) and Y-score (partner→ANKRD50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.461	+3.016	<.001	.018	3	4
COAD	ATM →	-0.579	-3.000	.001	.034	3	3
UCEC	FASN →	+0.239	+0.956	.018	.023	3	3
UCEC	GAPDH →	+0.414	+1.584	.002	.002	3	3
UCEC	PCNA →	+0.186	+2.807	<.001	<.001	3	3
UCEC	STAT3_pY705 →	-0.325	-1.449	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Caspase-7-cleavedD198 by ANKRD50 expression — COAD

Explore this box plot interactively →