ANKRD50

Across TCGA cell cohorts, ANKRD50 mutation is significantly associated with the RNA expression of many other genes, with 746 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD50-associated genes across cancer lineages are CPO, LARP1B, and C21orf91. Each is linked with ANKRD50 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD50-to-partner and partner-to-ANKRD50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPO grouped by ANKRD50-low versus ANKRD50-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD50→partner) and Y-score (partner→ANKRD50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CPO →	+0.049	+3.236	.002	.003	3	2
LARGE_INTESTINE	LARP1B →	+0.811	+3.459	<.001	.001	3	2
LARGE_INTESTINE	C21orf91 →	+0.710	+3.169	.001	.009	3	2
LARGE_INTESTINE	GNPDA2 →	+0.849	+3.234	<.001	.004	3	2
LARGE_INTESTINE	ABCE1 →	+0.656	+3.169	<.001	.009	3	2
LARGE_INTESTINE	DEFA3 →	+0.030	+2.678	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 746 associations by consensus.

CPO by ANKRD50 expression — BLOOD_Lymphoma

Explore this box plot interactively →