ANKRD44

Across TCGA pan-cancer cohorts, ANKRD44 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ANKRD44 data layer compared with 21 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ANKRD44 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANKRD44 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

COAD, HNSC, and LUAD are the cancer types where ANKRD44 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.879	1.000	.014	60	view →
HNSC	DFS	Median	II,III,IV	0.549	0.784	.006	16	view →
LUAD	DFS	Quartile	All	0.919	0.532	<.001	13	view →
PDAC	OS	Tertile	All	0.547	0.299	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ANKRD44–COAD (DFS)

Open the COAD breakdown →