ANKRD44

Across TCGA patient cohorts, ANKRD44 mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD44-associated genes across cancer lineages are 14-3-3_beta, GAPDH, and INPP4B. Each is linked with ANKRD44 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD44-to-partner and partner-to-ANKRD44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by ANKRD44-low versus ANKRD44-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD44→partner) and Y-score (partner→ANKRD44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.078	-1.880	.010	.014	3	2
UCEC	GAPDH →	+0.391	+1.999	.015	.008	3	2
UCEC	INPP4B →	-0.272	-1.925	.005	.004	3	2
UCEC	JNK_pT183_Y185 →	-0.171	-2.070	<.001	.001	3	2
UCEC	MEK1 →	+0.339	+2.137	.002	<.001	3	2
UCEC	PCNA →	+0.270	+1.999	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

14-3-3_beta by ANKRD44 expression — UCEC

Explore this box plot interactively →