ANKRD40CL

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD40CL mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD40CL-associated genes across cancer lineages are NUDT4P2, MIR6859-2, and RNA5SP414. Each is linked with ANKRD40CL in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD40CL-to-partner and partner-to-ANKRD40CL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUDT4P2 grouped by ANKRD40CL-low versus ANKRD40CL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD40CL→partner) and Y-score (partner→ANKRD40CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNUDT4P2 →+0.089+4.484<.001.00931
UCECMIR6859-2 →+0.687+4.690<.001.00331
UCECRNA5SP414 →+1.253+4.840<.001.00331
UCECHNRNPCL3 →+0.099+4.778<.001.00331
UCECMIR3619 →+1.056+4.188<.001.00931
UCECRNU6-1082P →+0.416+4.551<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

NUDT4P2 by ANKRD40CL expression — UCEC

Box plot of NUDT4P2 in ANKRD40CL-low vs ANKRD40CL-high samples in UCEC.

Explore this box plot interactively →

Exploration