ANKRD40

Across TCGA pan-cancer cohorts, ANKRD40 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ANKRD40 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ANKRD40 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANKRD40 expression acts as an unfavorable survival marker.

PDAC, HNSC, and GBM are the cancer types where ANKRD40 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	II,III,IV	0.419	0.909	.005	17	view →
HNSC	OS	Quartile	All	0.104	0.781	.045	12	view →
GBM	DFS	Median	All	0.294	0.447	.035	4	view →
LSCC	OS	Median	All	0.793	1.000	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ANKRD40–PDAC (DFS)

Open the PDAC breakdown →