ANKRD40

Across TCGA patient cohorts, ANKRD40 protein abundance is significantly associated with the RNA expression of many other genes, with 7,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANKRD40-associated genes across cancer lineages are RPRD1B, DHX40, and RPS6KB1. Each is linked with ANKRD40 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD40-to-partner and partner-to-ANKRD40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD40 versus RPRD1B in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD40→partner) and Y-score (partner→ANKRD40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPRD1B →	+0.507	+0.297	<.001	<.001	3	3
LSCC	DHX40 →	+0.878	+0.298	<.001	<.001	3	3
BRCA	RPS6KB1 →	+0.515	+0.394	<.001	<.001	3	3
BRCA	INTS2 →	+0.957	+0.666	<.001	<.001	3	3
BRCA	LRRC59 →	+0.732	+0.553	<.001	<.001	3	3
BRCA	UTP18 →	+0.746	+0.493	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,313 associations by consensus.

ANKRD40 vs RPRD1B — LSCC

Explore this scatter interactively →