ANKRD40

Across TCGA patient cohorts, ANKRD40 mutation is significantly associated with the RNA expression of many other genes, with 605 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD40-associated genes across cancer lineages are RN7SL383P, RNU6-467P, and RN7SKP221. Each is linked with ANKRD40 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD40-to-partner and partner-to-ANKRD40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL383P grouped by ANKRD40-low versus ANKRD40-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD40→partner) and Y-score (partner→ANKRD40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SL383P →	+0.276	+5.352	<.001	.005	3	3
GBM	RNU6-467P →	+0.502	+5.149	<.001	.007	3	2
BRCA	RN7SKP221 →	+0.099	+8.471	<.001	.005	3	2
BRCA	TRDD1 →	+1.367	+9.057	<.001	.003	3	2
STAD	RNU6-246P →	+0.515	+4.782	<.001	.003	3	2
SKCM	ACER2P1 →	+0.069	+4.661	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 605 associations by consensus.

RN7SL383P by ANKRD40 expression — GBM

Explore this box plot interactively →