ANKRD40

Across TCGA cell cohorts, ANKRD40 mutation is significantly associated with the RNA expression of many other genes, with 98 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ANKRD40-associated genes across cancer lineages are MS4A6E, GK2, and ASB11. Each is linked with ANKRD40 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD40-to-partner and partner-to-ANKRD40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A6E grouped by ANKRD40-low versus ANKRD40-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD40→partner) and Y-score (partner→ANKRD40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MS4A6E →	+0.238	+3.551	<.001	.009	3	2
OVARY	GK2 →	+0.004	+4.222	<.001	.006	3	2
BLOOD_Lymphoma	ASB11 →	+0.063	+4.350	<.001	.005	3	2
UPPER_AERODIGESTIVE_TRACT	ZNF804B →	+0.066	+4.510	<.001	.003	3	2
BLOOD_Lymphoma	OR52L1 →	+0.053	+4.191	<.001	.007	3	2
BLOOD_Lymphoma	OR56A5 →	+0.064	+4.927	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

MS4A6E by ANKRD40 expression — BLOOD_Leukemia

Explore this box plot interactively →