Across TCGA pan-cancer cohorts, ANKRD37 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ANKRD37’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ANKRD37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANKRD37 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.
KIRC, THCA, and LUAD are the cancer types where ANKRD37 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD37 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.