ANKRD36

Across TCGA patient cohorts, ANKRD36 mutation is significantly associated with the RNA expression of many other genes, with 2,734 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD36-associated genes across cancer lineages are ZIC2, MIR7159, and CCL5. Each is linked with ANKRD36 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD36-to-partner and partner-to-ANKRD36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZIC2 grouped by ANKRD36-low versus ANKRD36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD36→partner) and Y-score (partner→ANKRD36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZIC2 →	+1.500	+2.839	<.001	<.001	3	3
BRCA	MIR7159 →	+0.312	+3.732	<.001	<.001	3	2
UCEC	CCL5 →	+0.795	+1.954	.001	<.001	3	2
CESC	POTEF-AS1 →	+0.303	+4.384	<.001	.008	3	2
BLCA	MORC1-AS1 →	+0.055	+5.229	<.001	.002	3	2
UCEC	CRYBB2P1 →	+0.380	+1.699	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,734 associations by consensus.

ZIC2 by ANKRD36 expression — UCEC

Explore this box plot interactively →