ANKRD36

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD36 mutation is significantly associated with the RNA expression of many other genes, with 481 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD36-associated genes across cancer lineages are STRADA, AKT1, and LRCOL1. Each is linked with ANKRD36 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD36-to-partner and partner-to-ANKRD36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STRADA grouped by ANKRD36-low versus ANKRD36-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD36→partner) and Y-score (partner→ANKRD36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINSTRADA →+0.443+3.364.008.00233
SKINAKT1 →+0.697+3.451.001.00232
SKINLRCOL1 →+0.326+3.754<.001<.00132
SKINZNF407 →+0.385+3.082.009.00732
LARGE_INTESTINESIKE1 →+0.677+3.364.001.00232
BLOOD_LeukemiaCTSH →-2.596-3.459<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 481 associations by consensus.

STRADA by ANKRD36 expression — SKIN

Box plot of STRADA in ANKRD36-low vs ANKRD36-high samples in SKIN.

Explore this box plot interactively →

Exploration