Across TCGA patient cohorts, ANKRD35 protein abundance is significantly associated with the RNA expression of many other genes, with 3,939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD35-associated genes across cancer lineages are SNX10, BUB1B, and NDRG2. Each is linked with ANKRD35 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD35-to-partner and partner-to-ANKRD35 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD35→partner) and Y-score (partner→ANKRD35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX10 →	-1.026	-0.662	.001	.001	3	3
HNSC	BUB1B →	-0.833	-0.448	.002	.001	3	3
HNSC	NDRG2 →	+0.810	+0.553	<.001	<.001	3	3
UCEC	ASPM →	-0.993	-0.610	<.001	<.001	3	3
LSCC	E2F3 →	-0.396	-0.234	.003	.009	3	3
OV	COMP →	-2.509	-0.605	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,939 associations by consensus.

Exploration

ANKRD35 survival (RNA) · tumor vs normal (RNA) · all ANKRD35 data types