ANKRD35

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD35 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD35-associated genes across cancer lineages are JNK_pT183_Y185, AR, and Chk2_pT68. Each is linked with ANKRD35 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD35-to-partner and partner-to-ANKRD35 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD35→partner) and Y-score (partner→ANKRD35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECJNK_pT183_Y185 →-0.202-2.234.001.00232
UCECAR →-0.378-2.247.005.00132
SKCMChk2_pT68 →-0.186-2.000.007.03132
UCECeEF2 →+0.372+2.584.004.01032
UCECA-Raf_pS299 →-0.111-3.807.011<.00132
UCECGAPDH →+0.391+1.502.047.03032
Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration