ANKRD34C-AS1

Across TCGA pan-cancer cohorts, ANKRD34C-AS1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated ANKRD34C-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ANKRD34C-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANKRD34C-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and ESCA show a favorable association.

KIRC, KICH, and BLCA are the cancer types where ANKRD34C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.656	0.821	.005	54	view →
KICH	DFS	Tertile	All	0.237	0.860	<.001	45	view →
BLCA	DFS	Tertile	III,IV	0.070	0.495	<.001	36	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	27	view →
MESO	DFS	Tertile	III,IV	0.082	0.414	.007	27	view →
LGG	DFS	Tertile	All	0.818	0.646	.005	18	view →
ESCA	OS	Tertile	III,IV	0.755	0.354	.027	15	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ANKRD34C-AS1–KIRC (DFS)

Open the KIRC breakdown →