Across TCGA cell cohorts, ANKRD34B mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ANKRD34B-associated genes across cancer lineages are OR10G2, KLHL34, and OR4K1. Each is linked with ANKRD34B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD34B-to-partner and partner-to-ANKRD34B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD34B→partner) and Y-score (partner→ANKRD34B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10G2 →	+0.017	+5.022	<.001	.002	3	2
LARGE_INTESTINE	KLHL34 →	+0.111	+3.793	.001	.007	3	1
LUNG_NSCLC_LUAD	OR4K1 →	+0.022	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.022	+4.887	<.001	.009	3	1
SKIN	MRGPRE →	+0.022	+4.467	<.001	.004	3	1
SKIN	PRAMEF33 →	+0.009	+4.415	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ANKRD34B survival (RNA) · tumor vs normal (RNA) · all ANKRD34B data types