ANKRD33B

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD33B mutation is significantly associated with the mutation status of many other genes, with 2,190 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD33B-associated genes across cancer lineages are CADPS2, MSR1, and RIMBP2. Each is linked with ANKRD33B in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD33B-to-partner and partner-to-ANKRD33B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CADPS2 grouped by ANKRD33B-low versus ANKRD33B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD33B→partner) and Y-score (partner→ANKRD33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECADPS2 →+2.584+3.635<.001<.00114
LUNG_NSCLC_LUADMSR1 →+4.187+5.000.008.00813
LARGE_INTESTINERIMBP2 →+1.884+3.064.003.00313
LARGE_INTESTINECD93 →+2.415+3.510<.001<.00113
LARGE_INTESTINEHCN4 →+2.000+3.169.002.00213
BLOOD_LymphomaKCNH1 →+6.014+6.014.001.00113
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,190 associations by consensus.

CADPS2 by ANKRD33B expression — LARGE_INTESTINE

Box plot of CADPS2 in ANKRD33B-low vs ANKRD33B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration