ANKRD30BL

Across TCGA patient cohorts, ANKRD30BL mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD30BL-associated genes across cancer lineages are eIF4E, A-Raf_pS299, and Ku80. Each is linked with ANKRD30BL in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD30BL-to-partner and partner-to-ANKRD30BL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by ANKRD30BL-low versus ANKRD30BL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30BL→partner) and Y-score (partner→ANKRD30BL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.226	+3.169	.017	.019	3	1
UCEC	A-Raf_pS299 →	-0.174	-3.459	.001	.005	3	1
UCEC	Ku80 →	+0.376	+2.713	<.001	.003	3	1
UCEC	Myosin-IIa_pS1943 →	+0.218	+2.013	.019	.018	3	1
UCEC	Notch1 →	+0.165	+3.009	.009	.019	3	1
UCEC	p62 Lck ligand →	+0.477	+3.469	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

eIF4E by ANKRD30BL expression — UCEC

Explore this box plot interactively →