ANKRD26

Across TCGA patient cohorts, ANKRD26 protein abundance is significantly associated with the RNA expression of many other genes, with 2,828 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ANKRD26-associated genes across cancer lineages are RPL32P26, DOK3, and HLA-DQB1-AS1. Each is linked with ANKRD26 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD26-to-partner and partner-to-ANKRD26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD26 versus RPL32P26 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD26→partner) and Y-score (partner→ANKRD26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL32P26 →	-0.727	-0.462	.005	.004	3	2
LSCC	DOK3 →	-0.494	-0.262	.002	.003	3	2
BRCA	HLA-DQB1-AS1 →	-0.995	-0.556	.002	.001	3	2
BRCA	POU2F2 →	-0.882	-0.593	<.001	<.001	3	2
PDAC	LINC02182 →	-0.545	-0.645	.005	.002	3	2
LSCC	IGKV1OR2-3 →	-0.538	-0.389	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,828 associations by consensus.

ANKRD26 vs RPL32P26 — UCEC

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