ANKRD26

Across TCGA patient cohorts, ANKRD26 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD26-associated genes across cancer lineages are eIF4E, HER3_pY1289, and Caspase-7-cleavedD198. Each is linked with ANKRD26 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD26-to-partner and partner-to-ANKRD26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by ANKRD26-low versus ANKRD26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD26→partner) and Y-score (partner→ANKRD26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.199	+3.100	.001	<.001	3	4
UCEC	HER3_pY1289 →	+0.052	+1.085	.042	.025	3	3
COAD	Caspase-7-cleavedD198 →	+1.005	+3.008	.014	.019	3	3
BLCA	B-Raf →	-0.403	-2.987	.041	.035	3	2
UCEC	MEK1 →	+0.488	+2.369	<.001	<.001	3	2
UCEC	PCNA →	+0.229	+1.857	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

eIF4E by ANKRD26 expression — UCEC

Explore this box plot interactively →