ANKRD26

Across TCGA cell cohorts, ANKRD26 mutation is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD26-associated genes across cancer lineages are PRR23A, GSTT4, and C20orf173. Each is linked with ANKRD26 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD26-to-partner and partner-to-ANKRD26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23A grouped by ANKRD26-low versus ANKRD26-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD26→partner) and Y-score (partner→ANKRD26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PRR23A →	+0.033	+4.643	<.001	.008	3	2
BLOOD_Leukemia	GSTT4 →	+0.136	+2.681	<.001	.008	3	2
LUNG_NSCLC_LUAD	C20orf173 →	+0.029	+2.714	<.001	.007	3	2
LARGE_INTESTINE	PDS5A →	+0.446	+3.321	.007	.003	3	2
LARGE_INTESTINE	SERAC1 →	+0.486	+3.169	.009	.006	3	2
LARGE_INTESTINE	USP1 →	+0.552	+3.036	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

PRR23A by ANKRD26 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →