ANKRD22

Across TCGA patient cohorts, ANKRD22 mutation is significantly associated with the RNA expression of many other genes, with 1,538 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ANKRD22-associated genes across cancer lineages are MYO19, MAPK1, and CORO1C. Each is linked with ANKRD22 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD22-to-partner and partner-to-ANKRD22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYO19 grouped by ANKRD22-low versus ANKRD22-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD22→partner) and Y-score (partner→ANKRD22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MYO19 →	+0.647	+3.353	<.001	.005	3	2
SKCM	MAPK1 →	+0.714	+3.341	.001	.005	3	2
UCEC	CORO1C →	+0.839	+3.354	<.001	.005	3	2
SKCM	C1orf109 →	+0.749	+3.328	.002	.005	3	2
SKCM	SPIRE1 →	+1.142	+3.341	<.001	.005	3	2
SKCM	RNF14 →	+0.697	+3.328	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,538 associations by consensus.

MYO19 by ANKRD22 expression — SKCM

Explore this box plot interactively →