ANKRD20A4P

Across TCGA patient cohorts, ANKRD20A4P mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD20A4P-associated genes across cancer lineages are GAPDH, JNK2, and mTOR_pS2448. Each is linked with ANKRD20A4P in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD20A4P-to-partner and partner-to-ANKRD20A4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by ANKRD20A4P-low versus ANKRD20A4P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD20A4P→partner) and Y-score (partner→ANKRD20A4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.659	+3.169	.010	.018	3	1
UCEC	JNK2 →	+0.341	+3.179	<.001	.010	3	1
UCEC	mTOR_pS2448 →	-0.227	-3.302	.001	.010	3	1
UCEC	NF-kB-p65_pS536 →	-0.467	-2.999	.033	.035	3	1
UCEC	PDK1 →	+0.105	+2.820	.044	.035	3	1
UCEC	PKC-b-II_pS660 →	-0.408	-3.169	.002	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GAPDH by ANKRD20A4P expression — UCEC

Explore this box plot interactively →