ANKRD20A1

Across TCGA patient cohorts, ANKRD20A1 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD20A1-associated genes across cancer lineages are TTTY8, MIR320B1, and PLSCR5-AS1. Each is linked with ANKRD20A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD20A1-to-partner and partner-to-ANKRD20A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTTY8 grouped by ANKRD20A1-low versus ANKRD20A1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD20A1→partner) and Y-score (partner→ANKRD20A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TTTY8 →	+0.079	+9.057	<.001	.003	3	1
BRCA	MIR320B1 →	+0.517	+7.731	<.001	.009	3	1
BRCA	PLSCR5-AS1 →	+0.109	+8.471	<.001	.005	3	1
UCEC	GRAPL →	+0.138	+2.980	<.001	.006	3	1
UCEC	MIR550A1 →	+0.370	+3.277	.006	.002	3	1
UCEC	TRAJ57 →	+0.653	+2.997	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

TTTY8 by ANKRD20A1 expression — BRCA

Explore this box plot interactively →