ANKRD2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD2 mutation is significantly associated with the RNA expression of many other genes, with 1,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD2-associated genes across cancer lineages are RNA5SP436, RN7SL714P, and SNRPGP7. Each is linked with ANKRD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD2-to-partner and partner-to-ANKRD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by ANKRD2-low versus ANKRD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD2→partner) and Y-score (partner→ANKRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP436 →+0.354+3.030<.001.00133
UCECRN7SL714P →+0.118+3.367<.001<.00132
HNSCSNRPGP7 →+0.331+5.736<.001.00332
UCECRNU6-794P →+0.234+3.038<.001.00632
BRCARNU7-102P →+0.459+7.731<.001.00932
BLCAGPM6BP3 →+0.208+7.640<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,165 associations by consensus.

RNA5SP436 by ANKRD2 expression — UCEC

Box plot of RNA5SP436 in ANKRD2-low vs ANKRD2-high samples in UCEC.

Explore this box plot interactively →

Exploration