ANKRD2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,077 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD2-associated GO terms across cancer lineages are Regulation of macrophage colony-stimulating factor production, Signal release, and Mammary gland involution. Each is linked with ANKRD2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANKRD2-to-partner and partner-to-ANKRD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macrophage colony-stimulating factor production grouped by ANKRD2-low versus ANKRD2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD2→partner) and Y-score (partner→ANKRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERRegulation of macrophage colony-stimulating factor production →-0.913-1.078.007.00438
LUNG_NSCLC_LUSCSignal release →-0.075-1.053.001<.00138
LUNG_NSCLC_LUSCMammary gland involution →+0.194+0.926.003.00138
LUNG_NSCLC_LUSCRegulation of Ras protein signal transduction →-0.115-0.917<.001.00328
URINARY_TRACTHemidesmosome assembly →+0.260+1.271<.001.00137
STOMACHRegulation of osteoblast proliferation →+0.184+0.644.002.00637
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,077 associations by consensus.

Regulation of macrophage colony-stimulating factor production by ANKRD2 expression — LIVER

Box plot of Regulation of macrophage colony-stimulating factor production in ANKRD2-low vs ANKRD2-high samples in LIVER.

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Exploration