Across TCGA patient cohorts, ANKRD18DP mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD18DP-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and ERK2. Each is linked with ANKRD18DP in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD18DP-to-partner and partner-to-ANKRD18DP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD18DP→partner) and Y-score (partner→ANKRD18DP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.350	-3.584	.001	.002	3	1
UCEC	A-Raf_pS299 →	-0.175	-3.169	<.001	.019	3	1
UCEC	ERK2 →	+0.254	+2.115	.002	.019	3	1
UCEC	GATA6 →	-0.188	-3.155	.005	.018	3	1
UCEC	Heregulin →	-0.180	-2.115	<.001	.019	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.443	+2.331	.046	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ANKRD18DP survival (RNA) · tumor vs normal (RNA) · all ANKRD18DP data types