ANKRD18B

Across TCGA patient cohorts, ANKRD18B mutation is significantly associated with the RNA expression of many other genes, with 148 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD18B-associated genes across cancer lineages are PRELID3BP1, UBE2V1P5, and FBP2P1. Each is linked with ANKRD18B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD18B-to-partner and partner-to-ANKRD18B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRELID3BP1 grouped by ANKRD18B-low versus ANKRD18B-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD18B→partner) and Y-score (partner→ANKRD18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	PRELID3BP1 →	+0.115	+5.954	<.001	.002	3	1
SARC	UBE2V1P5 →	+0.152	+5.111	<.001	.008	3	1
SARC	FBP2P1 →	+0.116	+5.620	<.001	.004	3	1
UCEC	TRMU →	+0.515	+3.353	<.001	.005	3	1
UCEC	PARD6A →	+0.837	+3.329	<.001	.005	3	1
UCEC	CPQ →	-0.720	-3.576	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 148 associations by consensus.

PRELID3BP1 by ANKRD18B expression — SARC

Explore this box plot interactively →