ANKRD17

Across TCGA patient cohorts, ANKRD17 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD17-associated genes across cancer lineages are Cyclin-E2, ASNS, and 4E-BP1_pT70. Each is linked with ANKRD17 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD17-to-partner and partner-to-ANKRD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by ANKRD17-low versus ANKRD17-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD17→partner) and Y-score (partner→ANKRD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Cyclin-E2 →	+0.252	+2.178	.021	.035	3	4
UCEC	ASNS →	+0.306	+1.180	.001	.005	3	4
LUAD	4E-BP1_pT70 →	+0.313	+3.186	.001	.010	3	3
LUAD	4E-BP1_pS65 →	+0.302	+3.169	<.001	.019	3	2
LUSC	PAI-1 →	+0.592	+3.468	.048	.002	3	2
LUSC	TIGAR →	+0.166	+3.183	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Cyclin-E2 by ANKRD17 expression — COAD

Explore this box plot interactively →