ANKRD17

Across TCGA cell cohorts, ANKRD17 mutation is significantly associated with the mutation status of many other genes, with 5,858 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD17-associated genes across cancer lineages are LAMA5, LRBA, and PLXNC1. Each is linked with ANKRD17 in more than 6 cancer types. Because this analysis shows association rather than direction, both ANKRD17-to-partner and partner-to-ANKRD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LAMA5 grouped by ANKRD17-low versus ANKRD17-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD17→partner) and Y-score (partner→ANKRD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	LAMA5 →	+2.374	+4.099	.001	.001	1	7
UPPER_AERODIGESTIVE_TRACT	LRBA →	+3.954	+4.906	.001	.001	1	6
CNS	PLXNC1 →	+4.360	+2.877	.006	.006	1	6
UPPER_AERODIGESTIVE_TRACT	INSRR →	+4.539	+5.193	<.001	<.001	1	6
BLOOD_Lymphoma	VCAN →	+3.087	+2.584	<.001	<.001	1	6
STOMACH	SPEG →	+2.177	+2.949	.006	.006	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,858 associations by consensus.

LAMA5 by ANKRD17 expression — BREAST

Explore this box plot interactively →