ANKRD16

Across TCGA pan-cancer cohorts, ANKRD16 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ANKRD16 data layer compared with 25 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ANKRD16 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD16 expression acts as an unfavorable survival marker.

HNSC, LUAD, and COAD are the cancer types where ANKRD16 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.102	0.768	<.001	48	view →
LUAD	OS	Median	All	0.293	0.812	.009	9	view →
COAD	OS	Median	III,IV	0.157	0.791	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ANKRD16–HNSC (OS)

Open the HNSC breakdown →