ANKRD16

Across TCGA cell cohorts, ANKRD16 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,450 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANKRD16-associated GO terms across cancer lineages are Response to methylglyoxal, Cellular response to methylglyoxal, and Metanephric proximal tubule development. Each is linked with ANKRD16 in more than 10 cancer types. Because this analysis shows association rather than direction, both ANKRD16-to-partner and partner-to-ANKRD16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to methylglyoxal grouped by ANKRD16-low versus ANKRD16-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD16→partner) and Y-score (partner→ANKRD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Response to methylglyoxal →	+0.107	+0.519	<.001	<.001	3	11
CNS	Cellular response to methylglyoxal →	+0.107	+0.519	<.001	<.001	3	11
OESOPHAGUS	Metanephric proximal tubule development →	+0.201	+0.633	<.001	.002	3	11
LARGE_INTESTINE	Cellular detoxification of methylglyoxal →	+0.107	+0.428	<.001	.001	3	11
PANCREAS	IMP metabolic process →	+0.130	+0.585	<.001	.001	3	11
PANCREAS	Positive regulation of isotype switching to IgG isotypes →	+0.135	+0.793	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,450 associations by consensus.

Response to methylglyoxal by ANKRD16 expression — CNS

Explore this box plot interactively →