ANKRD13B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD13B mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD13B-associated genes across cancer lineages are IGFBP2, 14-3-3_beta, and eEF2. Each is linked with ANKRD13B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD13B-to-partner and partner-to-ANKRD13B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD13B→partner) and Y-score (partner→ANKRD13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIGFBP2 →-0.756-2.584<.001.01032
UCEC14-3-3_beta →-0.080-1.847.023.04931
UCECeEF2 →+0.272+2.000.031.00331
UCECEGFR_pY1068 →-0.255-2.000.003.00331
UCECeIF4E →+0.203+2.415.006.00331
UCECERK2 →+0.245+2.584<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration