ANKRD13A

Across TCGA patient cohorts, ANKRD13A mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD13A-associated genes across cancer lineages are ERK2, MEK1, and p38-MAPK_pT180_Y182. Each is linked with ANKRD13A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD13A-to-partner and partner-to-ANKRD13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by ANKRD13A-low versus ANKRD13A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD13A→partner) and Y-score (partner→ANKRD13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.161	+1.874	.029	.049	3	2
UCEC	MEK1 →	+0.411	+2.087	.003	.005	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.413	-2.807	.016	.003	3	2
UCEC	Shc_pY317 →	-0.154	-2.000	.008	.030	3	2
UCEC	ATM →	-0.467	-3.308	.007	.009	3	2
UCEC	eIF4E →	+0.168	+2.459	.038	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

ERK2 by ANKRD13A expression — UCEC

Explore this box plot interactively →