ANKRD12

Across TCGA patient cohorts, ANKRD12 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,309 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ANKRD12-associated proteins across cancer lineages are SEC63, ANKRD12_S1189, and KMT2E_S837. Each is linked with ANKRD12 in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKRD12-to-partner and partner-to-ANKRD12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD12 versus SEC63 in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD12→partner) and Y-score (partner→ANKRD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC63 →	-0.522	-0.592	<.001	<.001	3	5
LSCC	ANKRD12_S1189 →	+0.419	+0.333	<.001	.002	3	5
GBM	KMT2E_S837 →	+0.759	+0.511	<.001	<.001	3	5
OV	LIG3_S242 →	-0.589	-0.582	.006	.006	3	4
BRCA	POR →	-0.579	-0.577	<.001	<.001	3	4
COAD	MRPL47 →	-0.364	-0.518	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,309 associations by consensus.

ANKRD12 vs SEC63 — BRCA

Explore this scatter interactively →