ANKRD12

Across TCGA patient cohorts, ANKRD12 protein abundance is significantly associated with the RNA expression of many other genes, with 1,821 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANKRD12-associated genes across cancer lineages are RAB5IF, RRN3P2, and TWSG1. Each is linked with ANKRD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD12-to-partner and partner-to-ANKRD12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD12 versus RAB5IF in PDAC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD12→partner) and Y-score (partner→ANKRD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RAB5IF →	-0.740	-0.298	<.001	<.001	3	2
UCEC	RRN3P2 →	-0.386	-0.171	<.001	.009	3	2
BRCA	TWSG1 →	+0.732	+0.234	.001	.001	3	2
LSCC	DNAJA4 →	-0.662	-0.164	<.001	<.001	3	2
BRCA	ULK2 →	+0.663	+0.285	.001	<.001	3	2
LSCC	BCAP31P1 →	-0.625	-0.180	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,821 associations by consensus.

ANKRD12 vs RAB5IF — PDAC

Explore this scatter interactively →