ANKRD10-IT1

Across TCGA pan-cancer cohorts, ANKRD10-IT1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ANKRD10-IT1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ANKRD10-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANKRD10-IT1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

KIRC, ACC, and BLCA are the cancer types where ANKRD10-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.517	0.700	<.001	91	view →
ACC	DFS	Median	All	0.437	0.718	.003	50	view →
BLCA	OS	Tertile	II,III,IV	0.789	0.614	.001	47	view →
UVM	DFS	Quartile	III,IV	0.129	0.914	<.001	46	view →
HNSC	DFS	Median	IV	0.729	0.552	<.001	42	view →
MESO	DFS	Median	IV	0.206	0.472	.029	27	view →
THCA	DFS	Median	II,III,IV	0.856	0.947	.003	24	view →
LGG	DFS	Median	All	0.782	0.878	<.001	23	view →
READ	OS	Median	II,III,IV	1.000	0.842	.005	19	view →
COAD	DFS	Tertile	All	0.570	0.769	.007	19	view →
KICH	DFS	Median	II,III,IV	0.703	0.958	.011	18	view →
CESC	DFS	Quartile	All	0.624	0.851	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ANKRD10-IT1–KIRC (DFS)

Open the KIRC breakdown →