ANKRA2

Across TCGA patient cohorts, ANKRA2 protein abundance is significantly associated with the RNA expression of many other genes, with 610 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ANKRA2-associated genes across cancer lineages are DELE1, SDR39U1, and SRSF5. Each is linked with ANKRA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRA2-to-partner and partner-to-ANKRA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRA2 versus DELE1 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRA2→partner) and Y-score (partner→ANKRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DELE1 →	+0.758	+0.866	.002	<.001	3	2
LUAD	SDR39U1 →	+0.303	+0.307	.009	.003	3	1
LUAD	SRSF5 →	+0.417	+0.405	.002	.001	3	1
LUAD	PLTP →	-1.053	-0.371	.003	.005	3	1
LUAD	PGK1 →	-0.579	-0.387	.005	.003	3	1
LUAD	TSC22D1 →	+0.873	+0.334	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 610 associations by consensus.

ANKRA2 vs DELE1 — BRCA

Explore this scatter interactively →