ANKRA2

Across TCGA cell cohorts, ANKRA2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ANKRA2-associated genes across cancer lineages are GFRA4 and GSG1L2. Each is linked with ANKRA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRA2-to-partner and partner-to-ANKRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA4 grouped by ANKRA2-low versus ANKRA2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRA2→partner) and Y-score (partner→ANKRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GFRA4 →	+0.022	+5.169	<.001	.005	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GFRA4 by ANKRA2 expression — BREAST

Explore this box plot interactively →