ANKMY2

Across TCGA patient cohorts, ANKMY2 mutation is significantly associated with the RNA expression of many other genes, with 1,287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKMY2-associated genes across cancer lineages are HAUS1, SPC24, and TEDC2. Each is linked with ANKMY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKMY2-to-partner and partner-to-ANKMY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HAUS1 grouped by ANKMY2-low versus ANKMY2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKMY2→partner) and Y-score (partner→ANKMY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HAUS1 →	+0.604	+2.354	.002	.003	3	2
UCEC	SPC24 →	+0.786	+3.584	.001	.002	3	2
UCEC	TEDC2 →	+0.719	+3.724	<.001	<.001	3	2
UCEC	GFI1 →	+0.570	+3.021	<.001	<.001	3	2
UCEC	CTLA4 →	+1.016	+3.042	<.001	<.001	3	2
UCEC	PTTG1 →	+0.671	+3.467	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,287 associations by consensus.

HAUS1 by ANKMY2 expression — UCEC

Explore this box plot interactively →